Bioequivalence study of S-amlodipine Gentisate Conventional Versus new Formulation
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چکیده
منابع مشابه
Pharmacokinetic and bioequivalence study of a telmisartan/S-amlodipine fixed-dose combination (CKD-828) formulation and coadministered telmisartan and S-amlodipine in healthy subjects
Purpose A new fixed-dose combination (FDC) formulation of telmisartan 80 mg and S-amlodipine 5 mg (CKD-828) has been developed to increase convenience (as only one tablet is required per day) and improve treatment compliance. Methods The pharmacokinetic characteristics and tolerability of an FDC of telmisartan and S-amlodipine were compared to those after coadministration of the individual ag...
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The aim of this study was to formulate a film-coated Valsartan/Amlodipine (VS/AM) immediate release tablets and to evaluate their in vivo release profile. VS/AM core tablets were manufactured using dry granulation method. Opadry aqueous coating dispersion was used as film coating material. Dissolution of the film coated tablets was tested in 900 ml of 0.5% SLS media, bioequivalence of tablets w...
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This study was to investigate the efficiency of buccal dosage forms to deliver poor orally absorbed drugs. Two buccal gel formulations containing two gastrokinetic drugs with low oral bioavailability; domperidone and mosapride citrate; were tested against their market products. Twenty-four volunteers were enrolled in this study divided into two groups in a single dose, two treatment and two per...
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ژورنال
عنوان ژورنال: Journal of Korean Society for Clinical Pharmacology and Therapeutics
سال: 2008
ISSN: 1225-5467
DOI: 10.12793/jkscpt.2008.16.1.37